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Guidot DM

Physiol (Bethesda)

doi: 10.1016/j.cmet.2021.10.008 14 NobelsAvan MarckeCJordanBFVan HulMCaniPD

Conversely, within acidic tumor microenvironments, upregulated PPAR fuels cancer cell proliferation and invasion by enhancing FAO and lipid droplet (LD) accumulation, thereby supporting the energy demands of acid-adapted CRC cells (95)